A Comprehensive Guide to Mastering Autism

A Comprehensive Guide to Mastering Autism, Autoimmune, and Other
Neurological Disorders
(Formerly, "To Infuse or Not to Infuse" and "A Comprehensive Guide to
Managing Autism")
Willis S. Langford Copyright November 1999-2011 Mastering Autism.doc [May 28, 2011] A Comprehensive Guide to Mastering Autism TABLE OF CONTENTS
Subject
Page Introduction.........................................................
........................1
Immune 101
..................................................................52
Leaky Gut 84
Digestion 101......................
.......................................................87
Serotonin Connection 114
Healing the Leaky Gut 134
GABA 139
Candida 146
A Second Scenario 152
Copperheads 160
pH 164
Dr. Cheney's Oxygen Treatment 164
Transfer Factor 170
Negative Effects of Secretin 171
Hydrochloric Acid May be a Solution 174
Biochemical Observations 177
Solutions to the Problems 185
Histamine: Solution or Problem? 196
Enzymes: The Fountain of Life 198
Improved Nutrition Relieves Bowel and Infection 199
Care and Feeding of the Bowel 202
Some additional aids to overcome diarrhea: 206
Cod-liver Oil and Vitamin A 208
Bethanechol 212
What? Rickets? 218
Managing Fatty Acids 219
Medium Chain
Triglycerides........................................................
..229
Three Metabolic Types. 237
Tums Anyone? 237
Detoxification 101 241
Phenol-sulphotransferase (PST) 252
Vitamin A, GAGs, Measles, and PST 256
What Is MHPG? Why Should We Measure It? 272
Sulfation Ratio as a Measure of PST Activity 274
Mercury Poisoned. 279
Get the Lead Out 291
Acetaldehyde and NAD 298
Pyrroluria 300
The Thyroid: Metabolic Regulator 304
Forskolin: Poor Man's Secretin? 316
Demyelination 318
Fibroblast Growth Factor 328
Summary and Miscellaneous 329 A Comprehensive Guide to Mastering Autism Willis S. Langford Warning: Do not scan and read this paper piecemeal. It must be studied to
avoid mis-steps.
Use FIND, COPY, and PASTE to extract papagraphs of interest into a new,
shorter document for better correlation. Autism can be mastered! There are several very basic things discussed in
this paper that can be done at home with little or no expensive testing.
Foremost is the home testing for thyroid function discussed toward the end
of this paper, and support of thyroid function. The "unloading of the
donkey" is vital to possibly 80% of these troubled children for they are
poisoned, drowning in their own toxic wastes. Elimination of bowel
disorders is very first on the list of vital action. It is often as simple
as supplying a digestive enzyme supplement, or removing milk. A few
autistic children can be helped dramatically by medical procedures such as
an infusion of the intestinal hormone Secretin, but by and large, we are
dealing with a toxic condition requiring biochemical/dietary, not drug-
based, intervention. The need and the beneficial response to Secretin treatment, I think, are
dependent upon the amount of damage to the duodenum and small intestine,
and on the stomach's ability to produce adequate hydrochloric acid (HCl)
for proper digestion. Additionally, the WGA lectin of wheat
(gluten/gliadin) was shown to reduce Secretin production by 57%; however,
administration of 500 mg of N-acetylglucosamine twice a day (preferably at
beginning of the meal) completely suppressed this effect! Since these
factors largely determine proper digestion and assimilation, it is vital
that all systems be functioning optimally. Healing of the intestines,
including rebalancing of flora, is vital to health and well-being and
mental function. Release of Secretin is dependent on adequate HCl in the
chyme and upon the binding (neutralization) of Lectins found in grains and
legumes, in particular. Secretin is reduced in hypothyroid rats (Robberecht
et al, 1981); so, support the thyroid and bind (or remove) the lectins
(more later). Without adequate HCl, Secretin infusion can, at best, be only
partially effective in restoring digestion and proper physical and mental
function. HCl production and thyroid function are also very dependent on
adequate zinc levels, usually lacking in these children. This lack of zinc
may lead to skin conditions, loss of taste, neuropsychiatric symptoms,
sleep problems, and even the suppression of growth. An advanced zinc
deficiency is indicated by white specks or spots on fingernails. With
support for the thyroid, neutralizing of lectins (N-acetylglucosamine
neutralizes the WGA of wheat, and also the potato lectin), adequate zinc
and vitamin B6 intake, supplemental betaine hydrochloride (HCl - where
needed), DMAE, and/or Bethanechol, Secretin infusion may be totally
unnecessary. The path of autism is different for each child. Some are prone to seizures,
some are not; some behave aggressively, others are overly passive. However,
children with autism and with ADHD share several factors. "In one study,
66% of patients diagnosed with ADHD were found to be hypothyroid (at least
as many with autism are hypothyroid). Supporting their thyroid levels was
largely curative. Visual and auditory hallucinations may result from
altered perception and have been misdiagnosed as schizophrenia or psychosis
(or autism). Other behavioral symptoms have included fear - ranging from
mild anxiety to frank paranoia, mood swings, and aggression. Thyroid
hormone disorders may induce almost any psychiatric symptom or syndrome,
including rage"-Aronson and Dodman, 1997. Moods and behavior are largely influenced by the ratio of five central
nervous system chemicals known as amines. These include: norepinephrine
(noradrenaline), epinephrine (adrenaline), serotonin (5-HT), dopamine, and
phenylethylamine (PEA). The first three excite the CNS (central nervous
system) while the last two inhibit or modulate that excitement. The ratio
of these amines controls our levels of irritability. Kirov has observed an
association between severity of anxiety or depression and low plasma
Magnesium (Mg). Pliszka and Rogeness measured serum Mg in 165 boys admitted
to a psychiatric hospital and found low Mg levels to be associated with
dysphoric mood and sleep disorders. For a detailed study ask for "Managing
Vital Neurotransmitters". Additionally, there is a deep disturbance in their fatty acid metabolism
that impairs their utilization of amino acids, and often there is an
imbalance in their electrolytes. These can be symptoms of hypothyroidism!
Hsu studied the effects of only one nutrient deficiency, zinc, on the
levels of free amino acids in urine, plasma, and skin. When there was a
zinc deficiency, there was an inability for the body to metabolize all of
the available amino acids that were digested--thus they were excreted into
the urine as waste! Mercury in the system (from sources such as dental
amalgam "silver" fillings, vaccines, and Chlorox) excretes excessive
amounts of zinc, creating a hard to restore deficiency. While I would
suggest avoiding picolinate in other mineral chelates, it may be the answer
to this difficulty as it enhances zinc uptake by a factor of three.
However, an incidental and unexpected result of zinc picolinate
supplementation was an increase in plasma copper level from 155
µg./deciliter during ZnSO 4 treatment to 251 µg./deciliter after 10 weeks
of treatment with the picolinate. This is probably explainable on the basis
that additional free intestinal picolinic acid was available to complex
with the copper and thereby enhance its absorption. It is vital not to
imbalance the zinc:copper ratio. Zinc controls both the thyroid function
and the production of HCl for digestion. Electrolytes control what's called membrane traffic-what goes in and out of
cells. The delicate balance of electrolytes also controls the electrical
activity within the brain and heart. Additionally, it doesn't make any
difference what gets to that cell if it can't get into the cell. We know
that one of the major ways that you can affect cellular circulation is by
modulating the kinds of fatty acids that you eat. You increase receptor
sensitivity by increasing the fluidity of the cell membrane, which means
increasing the omega-3 content of the diet, because most people are very
deficient. The cell membranes are going to be a reflection of your dietary
fat, and that will determine their fluidity. Thus, providing other
nutritional supplements is relatively ineffective until the electrolyte
(sodium-potassium-magnesium-calcium) and fatty-acid imbalances are
corrected. You can actually make the membranes too fluid. If you eat and
incorporate too many omega-3 oils, then the membranes will become highly
oxidizable (so you must eat vitamin E and monounsaturates as well).
Practitioners suggest the extent of the nutritional pro